tumour-infiltrating lymphocyte

Cholangiocarcinoma (CCA) is one of major cancer in Northeast Thailand. Studies reveal tumours can induce immune response due to their altered protein products recognised as foreign bodies by the immune system. Tumour-infiltrating lymphocytes (TILs) can be assessed to represent the mentioned immune response. Recently, TILs are a potential predictive factor of prognosis in many solid tumours; still, data researched in CCA are limited. This study aimed to assess TILs in distal cholangiocarcinoma according to The International TILs Working Group (ITWG) guideline and to correlate it with...

Colorectal cancer prognosis is based on conventional histologic factors, i.e. subtype, grade, size, lymphovascolar invasion, perineural invasion and margin status. The 5th edition of WHO classification of digestive tumours newly updates histologic factors, i.e. growth pattern, tumour budding (TB), poorly differentiated clusters (PDC), tumour-infiltrating lymphocyte (TIL) and Crohn-like reaction (CLR). This study aimed to assess conventional histologic factors and newly updated histologic factors. Haematoxylin and eosin stained slides of 41 patients with stage II ...